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PXD043121

PXD043121 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleComparison of human and bat metabolism.
DescriptionCompared to other mammals, bats have increased longevity and higher resistance to cancer and infectious disease, in addition to their capacity for flight. This raises questions about bat metabolism. While prior studies have analyzed the metabolic requirements of flight, no study has integrated metabolomics, transcriptomics, and proteomics to characterize bat metabolism. In this work, we characterize fundamental differences in central metabolism between fibroblast cell lines from a black fruit bat (Pteropus alecto) and human, by analyzing multi-omics data via computational modelling of metabolic flux.
HostingRepositoryjPOST
AnnounceDate2024-06-20
AnnouncementXMLSubmission_2024-06-19_08:00:07.608.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterRadoslaw Sobota
SpeciesList scientific name: cellular organisms; NCBI TaxID: 131567;
ModificationListS-carboxamidomethyl-L-cysteine; alpha-amino acetylated residue; TMT6plex reporter+balance reagent N-acylated residue; TMT6plex reporter+balance reagent acylated N-terminal; L-methionine sulfoxide; deamidated L-glutamine; deamidated L-asparagine
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-06-19 22:14:18ID requested
12024-06-19 08:00:07announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: bat metabolism, fruit bat, electron transport chain components
Contact List
Prof. Koji Itahana
lab head
Radoslaw Sobota
contact affiliationIMCB A-STAR Singapore
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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