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PXD041001 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleArabidopsis thaliana polyQ - interactors
DescriptionWe've demonstrated that plants are resistant to the overexpression of polyglutamine (polyQ) extended proteins that cause protein aggregation and Huntington's disease in human cells. To investigate which proteins, maintain polyQ proteins correctly folded and avoid polyQ aggregates in plant cells. Our goal is to identify therapeutic candidate proteins that can potentially be used to treat Huntington's disease in human cell models.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
SpeciesList scientific name: Arabidopsis thaliana (Mouse-ear cress); NCBI TaxID: 3702;
ModificationListmonohydroxylated residue
InstrumentQ Exactive Plus
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-03-21 03:21:10ID requested
12023-07-17 04:32:14announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Arabidopsis thaliana, polyQ-extended proteins,Huntington's disease
Contact List
contact affiliationCECAD Forschungszentrum, Joseph-Stelzmann-Str. 26, 50931 Köln
contact emaildvilchez@uni-koeln.de
lab head
contact affiliationCECAD Research Center
contact emailproteomics-facility@uni-koeln.de
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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