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PXD040680 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTargeted Proteomics of Lung Squamous Cell Carcinomas
DescriptionTo address the complexity of cancer, liquid chromatography-multiple reaction monitoring mass spectrometry (LC-MRM) panels provide the capability to quantify clinical biomarkers and emerging protein markers to establish the context of tumor phenotypes that provide highly relevant supporting information. The resulting targeted proteomics data will empower translational researchers to move protein biomarker panels through the process from discovery to clinical use. Here, targeted proteomics panel measurements provide pathway-level evaluations of key biological drivers (e.g., EGFR signaling), phenotypes (e.g., EMT) and the ability to quantify specific drug targets within the context of a sample cohort of lung squamous cell carcinomas.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterJohn Koomen
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListCarbamidomethyl; Oxidation; Label:13C(6)15N(2); Label:13C(6)15N(4)
InstrumentTSQ Altis
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-03-07 23:04:58ID requested
12023-04-04 08:32:40announced
22023-07-09 23:04:56announced: Added PubMed Id
Publication List
Putty Reddy S, Alontaga AY, Welsh EA, Haura EB, Boyle TA, Eschrich SA, Koomen JM, Deciphering Phenotypes from Protein Biomarkers for Translational Research with PIPER. J Proteome Res, 22(6):2055-2066(2023) [pubmed]
Keyword List
submitter keyword: Lung Squamous Cell Carcinoma, multiple reaction monitoring
Contact List
John Koomen
contact affiliationMoffitt Cancer Center
contact emailjohn.koomen@moffitt.org
lab head
John Koomen
contact affiliationMoffitt Cancer Center
contact emailjohn.koomen@moffitt.org
dataset submitter
Full Dataset Link List
Panorama Public dataset URI