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PXD040620 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDIA proteomics on mouse tissue to investigate the GAPDH redox switch
DescriptionThe glycolytic enzyme GAPDH is equipped with a redox switch that rapidly and reversibly inactivates the enzyme in the presence of hydrogen peroxide. The physiological implications of the redox switch were investigated in C57BL/6NTac wildtype and GAPDH(T175A) knock-in mice generated by CRISPR/Cas9 genome editing.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJustus L.Großmann
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListiodoacetamide derivatized residue
InstrumenttimsTOF Pro 2
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-03-06 06:01:05ID requested
12023-04-10 09:03:26announced
Publication List
Keyword List
submitter keyword: heart, tissue, mus musculus, kidney, GAPDH,DIA-PASEF, mouse
Contact List
contact affiliationDepartment of Biochemistry, Charite Universitaetsmedizin Berlin, Germany
contact emailmarkus.ralser@charite.de
lab head
Justus L.Großmann
contact affiliationCharité Universitätsmedizin Berlin
contact emailjustus.grossmann@charite.de
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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