PXD039298
PXD039298 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Immunization with lytic polysaccharide monooxygenase CbpD induces protective immunity against Pseudomonas aeruginosa pneumonia |
Description | Bacterial lytic polysaccharide monooxygenases (LPMOs) are understudied in the context of infection disease. We demonstrated that Pseudomonas aeruginosa LPMO CbpD is a virulence determinant in pneumonia. Moreover, Mice immunized with CbpD generate robust antibody responses that provide protection against lethal lung infection |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_05:57:50.786.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jack-Ansgar Bruun |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Exploris 480 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-01-05 21:56:22 | ID requested | |
1 | 2023-07-26 00:23:51 | announced | |
2 | 2023-11-14 09:04:15 | announced | 2023-11-14: Updated project metadata. |
⏵ 3 | 2024-10-22 05:57:51 | announced | 2024-10-22: Updated project metadata. |
Publication List
Askarian F, Tsai CM, Cordara G, Zurich RH, Bj, å, nes E, Golten O, Vinther S, ø, rensen H, Kousha A, Meier A, Chikwati E, Bruun JA, Ludviksen JA, Choudhury B, Trieu D, Davis S, Edvardsen PKT, Mollnes TE, Liu GY, Krengel U, Conrad DJ, Vaaje-Kolstad G, Nizet V, pneumonia. Proc Natl Acad Sci U S A, 120(30):e2301538120(2023) [pubmed] |
10.1073/pnas.2301538120; |
Keyword List
submitter keyword: CbpD,LPMO, Pnemonia, Pseudomonas aeruginosa |
Contact List
Victor Nizet | |
---|---|
contact affiliation | Division of Host-Microbe Systems & Therapeutics, Department of Pediatrics, UC San Diego School of Medicine, La Jolla, CA, USA. |
contact email | vnizet@health.ucsd.edu |
lab head | |
Jack-Ansgar Bruun | |
contact affiliation | University of Tromsø |
contact email | jack-ansgar.bruun@uit.no |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD039298 |
PRIDE project URI |
Repository Record List
[ + ]