PXD039247

PXD039247 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	A hinge glycan regulates spike bending and impacts coronavirus infectivity
Description	Analysis of the structures and distributions of native spike conformations on vitrified human coronavirus NL63 (HCoV-NL63) virions without chemical fixation by cryogenic electron tomography (cryoET) and subtomogram averaging, along with site-specific glycan composition and occupancy determined by mass spectroscopy
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:27:09.483.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Peng Zhao
SpeciesList	scientific name: Cercopithecus aethiops (Green monkey) (Grivet); NCBI TaxID: 9534;
ModificationList	complex glycosylation
Instrument	Orbitrap Eclipse

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-01-04 04:02:18	ID requested
1	2024-01-26 09:46:24	announced
⏵ 2	2024-10-22 06:27:11	announced	2024-10-22: Updated project metadata.

Publication List

10.1038/s41467-023-42836-9;
Chmielewski D, Wilson EA, Pintilie G, Zhao P, Chen M, Schmid MF, Simmons G, Wells L, Jin J, Singharoy A, Chiu W, Structural insights into the modulation of coronavirus spike tilting and infectivity by hinge glycans. Nat Commun, 14(1):7175(2023) [pubmed]

10.1038/s41467-023-42836-9;

Chmielewski D, Wilson EA, Pintilie G, Zhao P, Chen M, Schmid MF, Simmons G, Wells L, Jin J, Singharoy A, Chiu W, Structural insights into the modulation of coronavirus spike tilting and infectivity by hinge glycans. Nat Commun, 14(1):7175(2023) [pubmed]

Keyword List

submitter keyword: spike,N-glycan, coronavirus

submitter keyword: spike,N-glycan, coronavirus

Contact List

Lance Wells
contact affiliation	Univeristy of Georgia
contact email	lwells@ccrc.uga.edu
lab head
Peng Zhao
contact affiliation	University of Georgia
contact email	pengzhao@uga.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD039247
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD039247

PRIDE project URI

Repository Record List

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