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PXD038776

PXD038776 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative LC-MS/MS Proteomics of human liver microsomes (healthy controls and normal-tumour from cancer patients)
DescriptionWe report quantification of proteins in human liver microsomal samples from 15 healthy volunteers and 18 patients with cancer in the liver (mainly, colorectal cancer liver metastasis). These data can be used in physiologically based pharmacokinetic models to predict appropriate drug doses in patients with cancer in their liver, especially colorectal cancer liver metastasis.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:47:44.772.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAreti-Maria Vasilogianni
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-12-12 22:54:37ID requested
12023-05-10 14:59:44announced
22023-11-14 08:47:46announced2023-11-14: Updated project metadata.
Publication List
Vasilogianni AM, Al-Majdoub ZM, Achour B, Peters SA, Rostami-Hodjegan A, Barber J, Proteomic quantification of receptor tyrosine kinases involved in the development and progression of colorectal cancer liver metastasis. Front Oncol, 13():1010563(2023) [pubmed]
Keyword List
submitter keyword: Human, healthy controls and normal-tumour livers from cancer patients, quantitative proteomics, LC-MS/MS
Contact List
Jill Barber
contact affiliationCentre for Applied Pharmacokinetic Research, Division of Pharmacy and Optometry, School of Health Sciences, Stopford Building, Room 2.026, Oxford Road, Manchester, M13 9PT.
contact emailjill.barber@manchester.ac.uk
lab head
Areti-Maria Vasilogianni
contact affiliationUniversity of Manchester
contact emailaretimaria.vasilogianni@manchester.ac.uk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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