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PXD038508 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDynamic Data Independent Acquisition Mass Spectrometry with Real-Time Retrospective Alignment
DescriptionWe report a data independent acquisition (DIA) strategy that dynamically adjusts the tandem mass spectrometry (MS/MS) windows during the chromatographic separation. The method focuses MS/MS acquisition on the most relevant mass range at each point in time – improving the quantitative sensitivity by increasing the time spent on each DIA window. We demonstrate an improved lower limit of quantification, on average, without sacrificing the number of peptides detected.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterLilian Heil
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListCarbamidomethyl; Label:13C(6)15N(2); Label:13C(6)15N(4)
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-12-01 18:52:26ID requested
12022-12-02 10:48:13announced
22023-09-18 21:39:57announced: Added PubMed Id
Publication List
Heil LR, Remes PM, Canterbury JD, Yip P, Barshop WD, Wu CC, MacCoss MJ, Dynamic Data-Independent Acquisition Mass Spectrometry with Real-Time Retrospective Alignment. Anal Chem, 95(32):11854-11858(2023) [pubmed]
Keyword List
submitter keyword: DIA, data independent acquisition
Contact List
Michael MacCoss
contact affiliationUniversity of Washington
contact emailmaccoss@uw.edu
lab head
Lilian Heil
contact affiliationUniversity of Washington
contact emaillheil2@uw.edu
dataset submitter
Full Dataset Link List
Panorama Public dataset URI