PXD033139

PXD033139 is an original dataset announced via ProteomeXchange.

Title	PKD autoinhibition in trans prevents activation loop autophosphorylation in cis
Description	HDX-MS analysis of the kinase domain of PKD1, showing that it forms an inactive dimer
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:42:16.150.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	John Burke
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	impact HD

Revision	Datetime	Status	ChangeLog Entry
0	2022-04-11 01:30:31	ID requested
1	2023-02-22 12:43:48	announced
2	2023-11-14 07:46:33	announced	2023-11-14: Updated project metadata.
⏵ 3	2024-10-22 05:42:18	announced	2024-10-22: Updated project metadata.

Reinhardt R, Hirzel K, Link G, Eisler SA, H, ä, gele T, Parson MAH, Burke JE, Hausser A, Leonard TA, . Proc Natl Acad Sci U S A, 120(7):e2212909120(2023) [pubmed]

10.1073/pnas.2212909120;

submitter keyword: PKD1,HDX-MS

Dr. John E. Burke
contact affiliation	University of Victoria
contact email	jeburke@uvic.ca
lab head
John Burke
contact affiliation	University of Victoria
contact email	jeburke@uvic.ca
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/02/PXD033139

PRIDE project URI

• PRIDE
  1. PXD033139
     1. Label: PRIDE project
     2. Name: PKD autoinhibition in trans prevents activation loop autophosphorylation in cis