Equid tapeworms have previously been considered to be of little pathological importance. Consequently, molecular characterisation of the proteome of Anoplocephala perfoliata has been previously neglected. However, associations with significant intestinal damage and colic cases demonstrate A. perfoliata infections pose a greater risk to equine health than previously considered. In the absence of commercial vaccines, the sole control option for equid tapeworms is via anthelmintic treatment. Limitations in control options pose a risk in anthelmintic resistance development and a reduced ability to sustain control of equid tapeworms. Proteomic analysis and characterisation of glutathione transferases (GST) have shown promise as novel anthelmintic or vaccine targets for improved helminth control. So whole worm proteome was analysed through 1DE and LC-MSMS to localise GST in the whole somatic proteome which may not be purified through GSH columns.