<<< Full experiment listing


PXD029483 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTargeted proteomic validation of dysregulated proteins in liver tissue of Labeo rohita after Aeromonas hydrophila infection
DescriptionAeromonas hydrophila (Ah) is an opportunistic Gram-negative bacterium and a serious global pathogen causing Motile Aeromonas Septicaemia (MAS) in fish and many other vertebrates. This study aimed at identifying the cellular proteins and processes altered by Ah infection in liver tissue of Labeo rohita, an important aquaculture species. Discovery based proteomics data could identify a panel of differentially expressed proteins (DEPs) between Control and AH condition (Ah infected group). Protein abundance changes in a few selected DEPs was then validated using Selected reaction monitoring (SRM) approach.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportsupported by repository but incomplete data and/or metadata
PrimarySubmitterMehar Un Nissa
SpeciesList scientific name: Labeo rohita; NCBI TaxID: 84645;
ModificationListCarbamidomethyl; Label:13C(6)15N(2)
InstrumentTSQ Altis
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-11-01 09:22:18ID requested
12023-05-02 09:08:41announced
Publication List
Nissa MU, Pinto N, Ghosh B, Singh U, Goswami M, Srivastava S, Proteomic analysis of liver tissue reveals Aeromonas hydrophila infection mediated modulation of host metabolic pathways in Labeo rohita. J Proteomics, 279():104870(2023) [pubmed]
Keyword List
submitter keyword: Aeromonas hydrophila, Liver proteomics, mass spectrometry, rohu, SRM
Contact List
Sanjeeva Srivastava
contact affiliationBiosciences and Bioengineering Department, IIT Bombay
contact emailsanjeeva@iitb.ac.in
lab head
Mehar Un Nissa
contact affiliationBiosciences and Bioengineering Department, IIT Bombay
contact emailkohlimeharunnissa@gmail.com
dataset submitter
Full Dataset Link List
Panorama Public dataset URI