PXD028651

PXD028651 is an original dataset announced via ProteomeXchange.

Title	A Prostate Cancer Proteomics Database for SWATH-MS based Protein Quantification
Description	Prostate cancer is the third most frequent cancer in men worldwide, with a notable increase in prevalence over the last two decades. The PSA is the only well-established protein biomarker for prostate cancer diagnosis, staging, and sur-veillance. It frequently leads to inaccurate diagnosis and overtreatment since it is an organ-specific biomarker rather than a tumour-specific biomarker. As a result, one of the primary goals of prostate cancer proteome research is to iden-tify novel biomarkers that can be used with or instead of PSA, particularly in non-invasive blood samples. Thousands of peptides or assays were detected in blood samples from patients with low to high-grade prostate cancer and healthy individuals, allowing data processing of sequential window acquisition of all theoretical mass spectra (SWATH-MS). By assisting in the detection of prostate cancer biomarkers in blood samples, this useful resource will improve our un-derstanding of the role of proteomics in prostate cancer diagnosis and risk assessment.
HostingRepository	PRIDE
AnnounceDate	2021-12-20
AnnouncementXML	Submission_2021-12-20_11:57:09.582.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	AMMARA MUAZZAM
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos; TripleTOF 6600

Revision	Datetime	Status	ChangeLog Entry
0	2021-09-20 02:59:06	ID requested
⏵ 1	2021-12-20 11:57:10	announced

Muazzam A, Chiasserini D, Kelsall J, Geifman N, Whetton AD, Townsend PA, A Prostate Cancer Proteomics Database for SWATH-MS Based Protein Quantification. Cancers (Basel), 13(21):(2021) [pubmed]

submitter keyword: Prostate cancer

spectral library

blood proteomics

protein

peptide

mass spectrometry

SWATH-MS

Paul Townsend
contact affiliation	University of Manchester
contact email	paul.townsend@manchester.ac.uk
lab head
AMMARA MUAZZAM
contact affiliation	University of Manchester
contact email	ammara.muazzam@postgrad.manchester.ac.uk
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD028651
     1. Label: PRIDE project
     2. Name: A Prostate Cancer Proteomics Database for SWATH-MS based Protein Quantification