PXD027641

PXD027641 is an original dataset announced via ProteomeXchange.

Title	SARS-CoV-2 variants of concern have acquired mutations associated with an increased spike cleavage
Description	Quantification of Spike cleavage across different Sars-Cov2 variants by partial reaction monitoring mass spectrometry
HostingRepository	PRIDE
AnnounceDate	2022-02-22
AnnouncementXML	Submission_2022-02-22_04:58:21.591.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Andrea Fossati
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-07-29 02:01:07	ID requested
⏵ 1	2022-02-22 04:58:22	announced

Escalera A, Gonzalez-Reiche AS, Aslam S, Mena I, Laporte M, Pearl RL, Fossati A, Rathnasinghe R, Alshammary H, van de Guchte A, Farrugia K, Qin Y, Bouhaddou M, Kehrer T, Zuliani-Alvarez L, Meekins DA, Balaraman V, McDowell C, Richt JA, Bajic G, Sordillo EM, Dejosez M, Zwaka TP, Krogan NJ, Simon V, Albrecht RA, van Bakel H, Garc, í, a-Sastre A, Aydillo T, Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission. Cell Host Microbe, 30(3):373-387.e7(2022) [pubmed]

ProteomeXchange project tag: Covid-19

submitter keyword: PRM, Sars-Cov2, Furin, GluC

Nevan Krogan
contact affiliation	6Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, USA
contact email	nevan.krogan@ucsf.edu
lab head
Andrea Fossati
contact affiliation	University of California San Francisco, Quantitative Biosciences Institute (QBI), San Francisco, CA, 94158, USA
contact email	andrea.fossati@ucsf.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD027641

PRIDE project URI

• PRIDE
  1. PXD027641
     1. Label: PRIDE project
     2. Name: SARS-CoV-2 variants of concern have acquired mutations associated with an increased spike cleavage