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PXD023855

PXD023855 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleRGI-GOLVEN signalling promotes FLS2 abundance to regulate plant immunity
DescriptionEndogenous plant signalling peptides regulate developmental and growth-related processes. Recent research indicates that some of these peptides are classified as phytocytokines as they have regulatory functions during plant immune responses. However, the mechanistic basis for phytocytokine-mediated immune modulation remains largely elusive. Here, we identify GOLVEN2 (GLV2) peptides as novel phytocytokines in Arabidopsis thaliana. By peptide application, precursor overexpression and loss-of-function studies we show that GLV2 enhances sensitivity of plants to elicitation with the bacterial flagellin epitope flg22. GLV2 is perceived by ROOT MERISTEM GROWTH FACTOR INSENSITIVE (RGI) receptors and RGI3 forms an flg22-induced complex with the flg22-receptor FLAGELLIN SENSING 2, suggesting that RGIs are part of activated pattern recognition receptor signalling platforms. GLV2 perception increases posttranscriptional FLS2 abundance and RGIs promote FLS2 protein accumulation. Thus, GLV-RGI signalling controls above ground plant immunity via a novel mechanism of phytocytokine activity.
HostingRepositoryPanoramaPublic
AnnounceDate2021-01-28
AnnouncementXMLSubmission_2021-01-28_05:36:08.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterChristina Ludwig
SpeciesList scientific name: Arabidopsis thaliana; NCBI TaxID: 3702;
ModificationListOxidation; Sulfo
InstrumentQ Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-01-27 20:09:51ID requested
12021-01-28 05:36:08announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: phytocytokines, targeted proteomics, plant immune response, GLV2 peptides
Contact List
Christina Ludwig
contact affiliationBavarian Center for Biomolecular Mass Spectrometry (BayBioMS), Technical University of Munich
contact emailtina.ludwig@tum.de
lab head
Christina Ludwig
contact affiliationBavarian Center for Biomolecular Mass Spectrometry (BayBioMS), Technical University of Munich
contact emailtina.ludwig@tum.de
dataset submitter
Full Dataset Link List
Panorama Public dataset URI