PXD021025 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Quantitative LC-MS/MS Proteomics of microsomal fractions from adult human livers |
Description | We report label-free and targeted quantification of xenobiotic metabolizing enzymes (XME) and transporters in 39 human liver microsomal samples. More than 2800 proteins were identified and quantified. These data can be used in physiologically based pharmacokinetic models for dosage regimen design and precision dosing. |
HostingRepository | PRIDE |
AnnounceDate | 2021-09-09 |
AnnouncementXML | Submission_2021-09-09_04:05:52.052.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Brahim Achour |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | LTQ Orbitrap Elite |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-08-20 08:37:17 | ID requested | |
⏵ 1 | 2021-09-09 04:05:52 | announced | |
Publication List
Al-Majdoub ZM, Achour B, Couto N, Howard M, Elmorsi Y, Scotcher D, Alrubia S, El-Khateeb E, Vasilogianni AM, Alohali N, Neuhoff S, Schmitt L, Rostami-Hodjegan A, Barber J, Mass spectrometry-based abundance atlas of ABC transporters in human liver, gut, kidney, brain and skin. FEBS Lett, 594(23):4134-4150(2020) [pubmed] |
Keyword List
submitter keyword: Human, adult livers, LC-MS/MS, quantitative proteomics |
Contact List
Jill Barber |
contact affiliation | Centre for Applied Pharmacokinetic Research, School of Health Sciences, The University of Manchester, UK |
contact email | jill.barber@manchester.ac.uk |
lab head | |
Brahim Achour |
contact affiliation | University of Manchester |
contact email | brahim.achour@manchester.ac.uk |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD021025 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD021025
- Label: PRIDE project
- Name: Quantitative LC-MS/MS Proteomics of microsomal fractions from adult human livers