PXD020284

PXD020284 is an original dataset announced via ProteomeXchange.

Title	Quantitative analysis of tyrosine phosphorylation from FFPE tissues reveals patient specific signaling networks
Description	The aim of this study was to characterize tyrosine phosphorylation from FFPE tissues. Global phosphoproteomics, global proteomics and tyrosine phosphorylation were measured using quantitative LC-MS/MS based on TMT labeling.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:28:53.601.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD020284
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Ishwar Kohale
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF; Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2020-07-09 17:22:15	ID requested
1	2021-09-09 07:00:16	announced
⏵ 2	2024-10-22 05:28:58	announced	2024-10-22: Updated project metadata.

Kohale IN, Burgenske DM, Mladek AC, Bakken KK, Kuang J, Boughey JC, Wang L, Carter JM, Haura EB, Goetz MP, Sarkaria JN, White FM, Quantitative Analysis of Tyrosine Phosphorylation from FFPE Tissues Reveals Patient-Specific Signaling Networks. Cancer Res, 81(14):3930-3941(2021) [pubmed]

10.1158/0008-5472.can-21-0214;

10.6019/PXD020284;

submitter keyword: LC-MS/MS, Phosphotyrosine, FFPE, Afatinib

Forest Michael White
contact affiliation	Department of Biological Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, United States
contact email	fwhite@mit.edu
lab head
Ishwar Kohale
contact affiliation	Department of Biological Engineering, Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA
contact email	ikohale@mit.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD020284

PRIDE project URI

• PRIDE
  1. PXD020284
     1. Label: PRIDE project
     2. Name: Quantitative analysis of tyrosine phosphorylation from FFPE tissues reveals patient specific signaling networks