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PXD020284

PXD020284 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative analysis of tyrosine phosphorylation from FFPE tissues reveals patient specific signaling networks
DescriptionThe aim of this study was to characterize tyrosine phosphorylation from FFPE tissues. Global phosphoproteomics, global proteomics and tyrosine phosphorylation were measured using quantitative LC-MS/MS based on TMT labeling.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:28:53.601.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD020284
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterIshwar Kohale
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListTMT6plex-126 reporter+balance reagent acylated residue; phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF; Q Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-07-09 17:22:15ID requested
12021-09-09 07:00:16announced
22024-10-22 05:28:58announced2024-10-22: Updated project metadata.
Publication List
Kohale IN, Burgenske DM, Mladek AC, Bakken KK, Kuang J, Boughey JC, Wang L, Carter JM, Haura EB, Goetz MP, Sarkaria JN, White FM, Quantitative Analysis of Tyrosine Phosphorylation from FFPE Tissues Reveals Patient-Specific Signaling Networks. Cancer Res, 81(14):3930-3941(2021) [pubmed]
10.1158/0008-5472.can-21-0214;
10.6019/PXD020284;
Keyword List
submitter keyword: LC-MS/MS, Phosphotyrosine, FFPE, Afatinib
Contact List
Forest Michael White
contact affiliationDepartment of Biological Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, United States
contact emailfwhite@mit.edu
lab head
Ishwar Kohale
contact affiliationDepartment of Biological Engineering, Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA
contact emailikohale@mit.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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