PXD019810 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | HDX-MS of VDR-RXR in complex with ZK168281 |
Description | Characterization of the interaction between the full nuclear receptor VDR-RXR heterodimer and VDR antagonist ZK168281 |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_05:16:48.419.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Anna Belorusova |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Synapt MS |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-06-16 08:30:44 | ID requested | |
1 | 2020-12-15 22:43:22 | announced | |
⏵ 2 | 2024-10-22 05:16:49 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.1038/s41467-020-20069-4; |
Rovito D, Belorusova AY, Chalhoub S, Rerra AI, Guiot E, Molin A, Linglart A, Rochel N, Laverny G, Metzger D, Cytosolic sequestration of the vitamin D receptor as a therapeutic option for vitamin D-induced hypercalcemia. Nat Commun, 11(1):6249(2020) [pubmed] |
Keyword List
submitter keyword: HDX-MS, nuclear receptors, antagonist |
Contact List
Tomas Leek |
contact affiliation | Medicinal Chemistry, Early Respiratory and Immunology, Biopharmaceuticals R&D, AstraZeneca |
contact email | Tomas.Leek@astrazeneca.com |
lab head | |
Anna Belorusova |
contact affiliation | Medicinal Chemistry, Early Respiratory and Inflammation, BioPharmaceuticals R&D, AstraZeneca |
contact email | anna.y.belorusova@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/12/PXD019810 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD019810
- Label: PRIDE project
- Name: HDX-MS of VDR-RXR in complex with ZK168281