<<< Full experiment listing

PXD019810

PXD019810 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHDX-MS of VDR-RXR in complex with ZK168281
DescriptionCharacterization of the interaction between the full nuclear receptor VDR-RXR heterodimer and VDR antagonist ZK168281
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:16:48.419.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAnna Belorusova
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentSynapt MS
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-06-16 08:30:44ID requested
12020-12-15 22:43:22announced
22024-10-22 05:16:49announced2024-10-22: Updated project metadata.
Publication List
10.1038/s41467-020-20069-4;
Rovito D, Belorusova AY, Chalhoub S, Rerra AI, Guiot E, Molin A, Linglart A, Rochel N, Laverny G, Metzger D, Cytosolic sequestration of the vitamin D receptor as a therapeutic option for vitamin D-induced hypercalcemia. Nat Commun, 11(1):6249(2020) [pubmed]
Keyword List
submitter keyword: HDX-MS, nuclear receptors, antagonist
Contact List
Tomas Leek
contact affiliationMedicinal Chemistry, Early Respiratory and Immunology, Biopharmaceuticals R&D, AstraZeneca
contact emailTomas.Leek@astrazeneca.com
lab head
Anna Belorusova
contact affiliationMedicinal Chemistry, Early Respiratory and Inflammation, BioPharmaceuticals R&D, AstraZeneca
contact emailanna.y.belorusova@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/12/PXD019810
PRIDE project URI
Repository Record List
[ + ]