<?xml version="1.0" encoding="UTF-8" standalone="yes"?> <ProteomeXchangeDataset id="PXD019362" formatVersion="1.4.0" xsi:noNamespaceSchemaLocation="proteomeXchange-1.4.0.xsd" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"> <CvList> <Cv fullName="PSI-MS" uri="https://raw.githubusercontent.com/HUPO-PSI/psi-ms-CV/master/psi-ms.obo" id="MS"/> <Cv fullName="PSI-MOD" uri="https://raw.githubusercontent.com/MICommunity/psidev/master/psi/mod/data/PSI-MOD.obo" id="MOD"/> <Cv fullName="UNIMOD" uri="http://www.unimod.org/obo/unimod.obo" id="UNIMOD"/> </CvList> <ChangeLog> <ChangeLogEntry date="2024-10-22">Updated project metadata.</ChangeLogEntry> </ChangeLog> <DatasetSummary announceDate="2024-10-22" hostingRepository="PRIDE" title="Towards understandingTissue Mϕ heterogeneity and functions using quantitative proteomics"> <Description>Resident macrophages are important for maintaining tissue homeostasis and for defence against infections, but their precise functions in different tissues are not fully elucidated.We have used high resolution quantitative proteomics to investigate the functions of splenic red pulp macrophages and peritoneal cavity macrophages in the steady-state. The validation of several proteins at cellular expression levels by the flow cytometry analysis was consistently in agreement with the proteomics data. Peritoneal macrophages were shown to be enriched in a number of key enzymes and metabolic pathways normally associated with the liver, such as metabolism of fructose, detoxification, nitrogen homeostasis and the urea cycle. Supporting observations in proteomics, we find that PM are able to utilise glutamine and glutamate which are rich in peritoneum for urea generation. In comparison, splenic red pulp macrophages were enriched in proteins important for adaptive immunity such as antigen presenting MHC molecules, in addition to proteins required for erythrocyte homeostasis and iron turnover. We also show that these tissue macrophages may utilise carbon and nitrogen substrates for different metabolic fates to support distinct tissue-specific roles. This study provides a valuable resource for biologists interested in the functions of tissue macrophages.</Description> <ReviewLevel> <cvParam cvRef="MS" accession="MS:1002854" name="Peer-reviewed dataset"/> </ReviewLevel> <RepositorySupport> <cvParam cvRef="MS" accession="MS:1002857" name="Unsupported dataset by repository"/> </RepositorySupport> </DatasetSummary> <DatasetIdentifierList> <DatasetIdentifier> <cvParam cvRef="MS" accession="MS:1001919" name="ProteomeXchange accession number" value="PXD019362"/> <cvParam cvRef="MS" accession="MS:1001921" name="ProteomeXchange accession number version number" value="2"/> </DatasetIdentifier> </DatasetIdentifierList> <DatasetOriginList> <DatasetOrigin> <cvParam cvRef="MS" accession="MS:1002868" name="Original data"/> </DatasetOrigin> </DatasetOriginList> <SpeciesList> <Species> <cvParam cvRef="MS" accession="MS:1001469" name="taxonomy: scientific name" value="Mus musculus (Mouse)"/> <cvParam cvRef="MS" accession="MS:1001467" name="taxonomy: NCBI TaxID" value="10090"/> </Species> </SpeciesList> <InstrumentList> <Instrument id="Instrument_1"> <cvParam cvRef="MS" accession="MS:1002523" name="Q Exactive HF"/> </Instrument> </InstrumentList> <ModificationList> <cvParam cvRef="MOD" accession="MOD:00397" name="iodoacetamide derivatized residue"/> </ModificationList> <ContactList> <Contact id="project_submitter"> <cvParam cvRef="MS" accession="MS:1000586" name="contact name" value="Manjula Nagala"/> <cvParam cvRef="MS" accession="MS:1000589" name="contact email" value="mnagala@dundee.ac.uk"/> <cvParam cvRef="MS" accession="MS:1000590" name="contact affiliation" value="Research Associate"/> <cvParam cvRef="MS" accession="MS:1002037" name="dataset submitter"/> </Contact> <Contact id="project_lab_head"> <cvParam cvRef="MS" accession="MS:1002332" name="lab head"/> <cvParam cvRef="MS" accession="MS:1000586" name="contact name" value="Professor Paul Crocker"/> <cvParam cvRef="MS" accession="MS:1000589" name="contact email" value="p.r.crocker@dundee.ac.uk"/> <cvParam cvRef="MS" accession="MS:1000590" name="contact affiliation" value="Professor of Glycoimmunology"/> </Contact> </ContactList> <PublicationList> <Publication id="pending"> <cvParam cvRef="MS" accession="MS:1002858" name="Dataset with its publication pending"/> </Publication> </PublicationList> <KeywordList> <cvParam cvRef="MS" accession="MS:1001925" name="submitter keyword" value="tissue,Mouse, macrophages, LCMSMS"/> </KeywordList> <FullDatasetLinkList> <FullDatasetLink> <cvParam cvRef="MS" accession="MS:1002852" name="Dataset FTP location" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362"/> </FullDatasetLink> <FullDatasetLink> <cvParam cvRef="MS" accession="MS:1001930" name="PRIDE project URI" value="http://www.ebi.ac.uk/pride/archive/projects/PXD019362"/> </FullDatasetLink> </FullDatasetLinkList> <DatasetFileList> <DatasetFile id="FILE_1" name="MN-WT2-Frac9.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT2-Frac9.raw"/> </DatasetFile> <DatasetFile id="FILE_2" name="MN-WT2-Frac-2.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT2-Frac-2.raw"/> </DatasetFile> <DatasetFile id="FILE_3" name="MN-2-Frac-1.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-2-Frac-1.raw"/> </DatasetFile> <DatasetFile id="FILE_4" name="MN-WT1-Frac6.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT1-Frac6.raw"/> </DatasetFile> <DatasetFile id="FILE_5" name="modificationSpecificPeptides.txt"> <cvParam cvRef="MS" accession="MS:1002849" name="Search engine output file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/modificationSpecificPeptides.txt"/> </DatasetFile> <DatasetFile id="FILE_6" name="MN-2-Frac-8.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-2-Frac-8.raw"/> </DatasetFile> <DatasetFile id="FILE_7" name="Proteomicanalysisresultcopynumber_Peritoneal_Spleenicmacrophage.txt"> <cvParam cvRef="MS" accession="MS:1002849" name="Search engine output file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/Proteomicanalysisresultcopynumber_Peritoneal_Spleenicmacrophage.txt"/> </DatasetFile> <DatasetFile id="FILE_8" name="MN-1-Frac-3.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-1-Frac-3.raw"/> </DatasetFile> <DatasetFile id="FILE_9" name="MN-1-Frac-5.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-1-Frac-5.raw"/> </DatasetFile> <DatasetFile id="FILE_10" name="MN-1-Frac-6.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-1-Frac-6.raw"/> </DatasetFile> <DatasetFile id="FILE_11" name="MN-WT1-Frac-3.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT1-Frac-3.raw"/> </DatasetFile> <DatasetFile id="FILE_12" name="MN-WT1-Frac-2.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT1-Frac-2.raw"/> </DatasetFile> <DatasetFile id="FILE_13" name="parameters.txt"> <cvParam cvRef="MS" accession="MS:1002849" name="Search engine output file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/parameters.txt"/> </DatasetFile> <DatasetFile id="FILE_14" name="MN-WT1-Frac9.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT1-Frac9.raw"/> </DatasetFile> <DatasetFile id="FILE_15" name="MN-3-Frac-5.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-3-Frac-5.raw"/> </DatasetFile> <DatasetFile id="FILE_16" name="MN-WT1-Frac-4.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT1-Frac-4.raw"/> </DatasetFile> <DatasetFile id="FILE_17" name="MN-1-Frac-10.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-1-Frac-10.raw"/> </DatasetFile> <DatasetFile id="FILE_18" name="MN-WT2-Frac6.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT2-Frac6.raw"/> </DatasetFile> <DatasetFile id="FILE_19" name="MN-4-Frac-5.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-4-Frac-5.raw"/> </DatasetFile> <DatasetFile id="FILE_20" name="MN-2-Frac-9.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-2-Frac-9.raw"/> </DatasetFile> <DatasetFile id="FILE_21" name="MN-WT1-Frac7.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT1-Frac7.raw"/> </DatasetFile> <DatasetFile id="FILE_22" name="MN-WT3-Frac8.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT3-Frac8.raw"/> </DatasetFile> <DatasetFile id="FILE_23" name="MN-WT3-Frac10.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT3-Frac10.raw"/> </DatasetFile> <DatasetFile id="FILE_24" name="msmsScans.txt"> <cvParam cvRef="MS" accession="MS:1002849" name="Search engine output file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/msmsScans.txt"/> </DatasetFile> <DatasetFile id="FILE_25" name="MN-4-Frac-6.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-4-Frac-6.raw"/> </DatasetFile> <DatasetFile id="FILE_26" name="MN-1-Frac-4.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-1-Frac-4.raw"/> </DatasetFile> <DatasetFile id="FILE_27" name="MN-4-Frac-8.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-4-Frac-8.raw"/> </DatasetFile> <DatasetFile id="FILE_28" name="MN-1-Frac-9.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-1-Frac-9.raw"/> </DatasetFile> <DatasetFile id="FILE_29" name="MN-4-Frac-10.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-4-Frac-10.raw"/> </DatasetFile> <DatasetFile id="FILE_30" name="MN-3-Frac-10.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-3-Frac-10.raw"/> </DatasetFile> <DatasetFile id="FILE_31" name="MN-2-Frac-3.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-2-Frac-3.raw"/> </DatasetFile> <DatasetFile id="FILE_32" name="MN-WT3-Frac-1.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT3-Frac-1.raw"/> </DatasetFile> <DatasetFile id="FILE_33" name="MN-1-Frac-1.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-1-Frac-1.raw"/> </DatasetFile> <DatasetFile id="FILE_34" name="MN-WT1-Frac-1.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT1-Frac-1.raw"/> </DatasetFile> <DatasetFile id="FILE_35" name="MN-3-Frac-7.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-3-Frac-7.raw"/> </DatasetFile> <DatasetFile id="FILE_36" name="MN-1-Frac-8.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-1-Frac-8.raw"/> </DatasetFile> <DatasetFile id="FILE_37" name="MN-2-Frac-10.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-2-Frac-10.raw"/> </DatasetFile> <DatasetFile id="FILE_38" name="MN-3-Frac-9.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-3-Frac-9.raw"/> </DatasetFile> <DatasetFile id="FILE_39" name="MN-4-Frac-1.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-4-Frac-1.raw"/> </DatasetFile> <DatasetFile id="FILE_40" name="peptides.txt"> <cvParam cvRef="MS" accession="MS:1002849" name="Search engine output file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/peptides.txt"/> </DatasetFile> <DatasetFile id="FILE_41" name="MN-WT1-Frac-5.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT1-Frac-5.raw"/> </DatasetFile> <DatasetFile id="FILE_42" name="MN-WT2-Frac-3.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT2-Frac-3.raw"/> </DatasetFile> <DatasetFile id="FILE_43" name="MN-WT2-Frac10.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT2-Frac10.raw"/> </DatasetFile> <DatasetFile id="FILE_44" name="MN-WT2-Frac8.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT2-Frac8.raw"/> </DatasetFile> <DatasetFile id="FILE_45" name="MN-3-Frac-4.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-3-Frac-4.raw"/> </DatasetFile> <DatasetFile id="FILE_46" name="MN-4-Frac-3.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-4-Frac-3.raw"/> </DatasetFile> <DatasetFile id="FILE_47" name="MN-2-Frac-7.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-2-Frac-7.raw"/> </DatasetFile> <DatasetFile id="FILE_48" name="MN-3-Frac-8.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-3-Frac-8.raw"/> </DatasetFile> <DatasetFile id="FILE_49" name="MN-WT3-Frac7.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT3-Frac7.raw"/> </DatasetFile> <DatasetFile id="FILE_50" name="MN-WT3-Frac6.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT3-Frac6.raw"/> </DatasetFile> <DatasetFile id="FILE_51" name="MN-3-Frac-2.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-3-Frac-2.raw"/> </DatasetFile> <DatasetFile id="FILE_52" name="MN-1-Frac-2.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-1-Frac-2.raw"/> </DatasetFile> <DatasetFile id="FILE_53" name="allPeptides.txt"> <cvParam cvRef="MS" accession="MS:1002849" name="Search engine output file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/allPeptides.txt"/> </DatasetFile> <DatasetFile id="FILE_54" name="MN-WT2-Frac7.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT2-Frac7.raw"/> </DatasetFile> <DatasetFile id="FILE_55" name="MN-WT3-Frac9.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT3-Frac9.raw"/> </DatasetFile> <DatasetFile id="FILE_56" name="msms.txt"> <cvParam cvRef="MS" accession="MS:1002849" name="Search engine output file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/msms.txt"/> </DatasetFile> <DatasetFile id="FILE_57" name="MN-2-Frac-4.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-2-Frac-4.raw"/> </DatasetFile> <DatasetFile id="FILE_58" name="MN-2-Frac-5.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-2-Frac-5.raw"/> </DatasetFile> <DatasetFile id="FILE_59" name="MN-WT3-Frac-4.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT3-Frac-4.raw"/> </DatasetFile> <DatasetFile id="FILE_60" name="MN-4-Frac-7.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-4-Frac-7.raw"/> </DatasetFile> <DatasetFile id="FILE_61" name="MN-WT2-Frac-5.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT2-Frac-5.raw"/> </DatasetFile> <DatasetFile id="FILE_62" name="MN-WT3-Frac-2.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT3-Frac-2.raw"/> </DatasetFile> <DatasetFile id="FILE_63" name="MN-WT2-Frac-1.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT2-Frac-1.raw"/> </DatasetFile> <DatasetFile id="FILE_64" name="MN-WT2-Frac-4.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT2-Frac-4.raw"/> </DatasetFile> <DatasetFile id="FILE_65" name="MN-WT3-Frac-5.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT3-Frac-5.raw"/> </DatasetFile> <DatasetFile id="FILE_66" name="MN-4-Frac-4.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-4-Frac-4.raw"/> </DatasetFile> <DatasetFile id="FILE_67" name="MN-3-Frac-6.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-3-Frac-6.raw"/> </DatasetFile> <DatasetFile id="FILE_68" name="MN-4-Frac-2.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-4-Frac-2.raw"/> </DatasetFile> <DatasetFile id="FILE_69" name="proteinGroups.txt"> <cvParam cvRef="MS" accession="MS:1002849" name="Search engine output file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/proteinGroups.txt"/> </DatasetFile> <DatasetFile id="FILE_70" name="MN-3-Frac-1.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-3-Frac-1.raw"/> </DatasetFile> <DatasetFile id="FILE_71" name="mzRange.txt"> <cvParam cvRef="MS" accession="MS:1002849" name="Search engine output file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/mzRange.txt"/> </DatasetFile> <DatasetFile id="FILE_72" name="MN-4-Frac-9.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-4-Frac-9.raw"/> </DatasetFile> <DatasetFile id="FILE_73" name="OxidationMSites.txt"> <cvParam cvRef="MS" accession="MS:1002849" name="Search engine output file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/OxidationMSites.txt"/> </DatasetFile> <DatasetFile id="FILE_74" name="MN-2-Frac-6.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-2-Frac-6.raw"/> </DatasetFile> <DatasetFile id="FILE_75" name="MN-3-Frac-3.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-3-Frac-3.raw"/> </DatasetFile> <DatasetFile id="FILE_76" name="evidence.txt"> <cvParam cvRef="MS" accession="MS:1002849" name="Search engine output file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/evidence.txt"/> </DatasetFile> <DatasetFile id="FILE_77" name="MN-WT1-Frac8.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT1-Frac8.raw"/> </DatasetFile> <DatasetFile id="FILE_78" name="MN-WT1-Frac10.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT1-Frac10.raw"/> </DatasetFile> <DatasetFile id="FILE_79" name="MN-2-Frac-2.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-2-Frac-2.raw"/> </DatasetFile> <DatasetFile id="FILE_80" name="msScans.txt"> <cvParam cvRef="MS" accession="MS:1002849" name="Search engine output file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/msScans.txt"/> </DatasetFile> <DatasetFile id="FILE_81" name="MN-1-Frac-7.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-1-Frac-7.raw"/> </DatasetFile> <DatasetFile id="FILE_82" name="MN-WT3-Frac-3.raw"> <cvParam cvRef="MS" accession="MS:1002846" name="Associated raw file URI" value="ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD019362/MN-WT3-Frac-3.raw"/> </DatasetFile> </DatasetFileList> <RepositoryRecordList> <RepositoryRecord name="Towards understandingTissue Mϕ heterogeneity and functions using quantitative proteomics" label="PRIDE project" recordID="PXD019362" repositoryID="PRIDE" uri="http://www.ebi.ac.uk/pride/archive/projects/PXD019362"/> </RepositoryRecordList> </ProteomeXchangeDataset>