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PXD018874 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHigh-throughput proteomics platform for clinical applications
DescriptionClinical proteomics holds the promise to accelerate the discovery of disease biomarkers, as well as to predict disease trajectories. Here we present a new platform for high-throughput plasma and serum proteomics, which combines an automated sample preparation workflow, robust high-flow liquid chromatography, and an optimized SWATH-MS acquisition scheme as well as data processing workflow. The process requires as little as 5uL serum or plasma and makes use of fast 5-minute chromatographic gradients. The dataset shows the robustness and precision of the workflow and consists of commercial plasma and serum samples that were distributed in 4 different 96 well plates and injected within a sample series of 417 serum injections. Further, the dataset includes of injections of a single sample (pooled from 32 prepared commercial serum samples) every 10 injections.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterChristoph Messner
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumentTripleTOF 6600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-04-28 16:51:02ID requested
12020-06-09 06:23:03announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: High-throughput proteomics, plasma, serum, clinical proteomics
Contact List
Markus Ralser
contact affiliationCharite- Universitaetsmedizin Berlin, 10117 Berlin, Germany
contact emailmarkus.ralser@charite.de
lab head
Christoph Messner
contact affiliationFrancis Crick Institute
contact emailchristoph.messner@crick.ac.uk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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