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PXD018343 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteome and PTMs analyses of mammary CAFs
DescriptionTo understand the molecular mechanisms that underpin pro-tumourigenic functions of cancer-associated fibroblasts (CAFs) we compared the proteome, acetylome, phosphoproteome of human immortalised breast cancer CAFs with those of the normal mammary fibroblasts that they were generated from. Based on the results obtained, we have also analysed proteome changes when CAFs were treated with the P300/CBP inhibitor c646.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSara Zanivan
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListphosphorylated residue; acetylated residue
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-04-03 00:15:14ID requested
12022-04-10 02:22:53announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Human, breast cancer, cancer-associated fibroblasts, epigenetics, acetylome, phosphoproteome, proteome
Contact List
Sara Zanivan
contact affiliationCRUK Beatson Institute
contact emails.zanivan@beatson.gla.ac.uk
lab head
Sara Zanivan
contact affiliationCRUK Beatson Institute Tumour Microenvironment & Proteomics
contact emails.zanivan@beatson.gla.ac.uk
dataset submitter
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Dataset FTP location
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