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PXD015578

PXD015578 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleAlzheimer stage proteomics study
DescriptionThis project aims to study the pathological role of Extracellular vesicles (EVs) in human brain and the correlation between EVs secretion with whole brain proteome. EVs are extracted from human brain tissue of Alzheimer dementia (AD) patients, VaD patients and age matched healthy controls using PROSPR method. Alzheimer patients includes stage3 (AD3), stage4 (AD4), stage5 (AD5) and stage6 (AD6). Whole brain proteome are performed simultaneously. Proteins associated with pre-symptomatic AD, AD progression and other pathological ways are analysed. The potential targets are further validated with MRM approach
HostingRepositoryPRIDE
AnnounceDate2020-05-04
AnnouncementXMLSubmission_2020-05-04_10:10:08.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterXue Guo
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; deamidated residue
InstrumentQ Exactive; LTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-09-25 04:00:22ID requested
12020-05-04 10:10:10announced
Publication List
Dataset with its publication pending
Keyword List
curator keyword: Biomedical
submitter keyword: Human, brain
Contact List
Sze Siu Kwan
contact affiliationNanyang Technological University
contact emailsksze@ntu.edu.sg
lab head
Xue Guo
contact affiliationNTU
contact emailGUOX0016@E.NTU.EDU.SG
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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