Despite direct or indirect efforts of proteomic community, the fraction of blind spots on the protein map is still significant. Almost 10% (?) of human master protein has no experimental validation up to now. Apparently, proteomics has reached the stage where all easy scores are achieved (?), and every next identification requires more intension and curiosity in expansion of unusual types of biomaterial and/or conditions. In this article we discuss the current state of missing proteins search conducted by eclectic Russian Consortium in frame of C-HPP. We accumulated various data, obtained by Russian Proteomic Consortium.