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PXD013427 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLysine acetylation of microbiome
DescriptionThis project study and comprehensively characterize the lysine acetyltion in the human gut microbiome using antibody-based enrichment strategry and Orbitrap mass spectrometer. The technique has also been applied to study the microbiome in pediatric Crohn's disease and control subjects in order to understand the functional alterations of microbiome in IBD.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterXu Zhang
SpeciesList scientific name: gut metagenome; NCBI TaxID: 749906;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-04-09 07:18:20ID requested
12020-07-07 22:27:39announced
22020-09-11 03:38:58announced2020-09-11: Updated publication reference for PubMed record(s): 32807798.
Publication List
Zhang X, Ning Z, Mayne J, Yang Y, Deeke SA, Walker K, Farnsworth CL, Stokes MP, Couture JF, Mack D, Stintzi A, Figeys D, Widespread protein lysine acetylation in gut microbiome and its alterations in patients with Crohn's disease. Nat Commun, 11(1):4120(2020) [pubmed]
Keyword List
submitter keyword: microbiome, gut, acetylation, PTM, Crohn's disease
Contact List
Daniel Figeys
contact affiliationUniversity of Ottawa
contact emaildfigeys@uottawa.ca
lab head
Xu Zhang
contact affiliationUniversity of Ottawa
contact emailcheuzhang@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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