White muscle samples from juvenile Pacific halibut were analyzed in discovery-driven proteomics to investigate the effects of temperature-induced growth manipulations and to identify protein markers of somatic growth. Juvenile Pacific halibut were either acclimated to 2C (low temperature) and 9C (control temperature) to elicit growth suppression and also initially acclimated to 2C and subsequently transferred to 9C to elicit growth compensation. This project was led by Josep Planas at the International Pacific Halibut Commission.