Update publication information. In Saccharomyces cerevisiae, Atg9 is an important AuTophaGy-related (Atg) protein, plays critical roles in regulating macroautophagy/autophagy, and physically interacts with hundreds of proteins. How Atg9 interacting partners are synergistically orchestrated in autophagy are unclear. Here, we conducted a transcriptomic and proteomic profiling of Atg9-dependent molecular landscapes during nitrogen starvation-induced autophagy.