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PXD008450 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTissue Microfibril Comparison
DescriptionFibrillin microfibrils are large supramolecular ECM assemblies which play different functional roles in different tissues. We aim to compare the ultrastructure and biological composition of fibrillin microfibrils purified from human eye, skin and cultured dermal fibroblasts. This will allow us to understand whether these their structure and compositions have evolved to suit the functions they play in different tissues.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterAlexander Eckersley
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListOxidation; Carbamidomethyl
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-12-14 02:20:09ID requested
12018-02-16 07:52:08announced
22018-02-23 04:21:12announcedUpdated publication reference for PubMed record(s): 29453284.
Publication List
Eckersley A, Mellody KT, Pilkington S, Griffiths CEM, Watson REB, O'Cualain R, Baldock C, Knight D, Sherratt MJ, Structural and compositional diversity of fibrillin microfibrils in human tissues. J Biol Chem, 293(14):5117-5133(2018) [pubmed]
Keyword List
curator keyword: Biological
submitter keyword: Human, fibrillin, collagen, microfibril, LC-MS/MS, AFM
Contact List
Michael Sherratt
contact affiliationDivision of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK
contact emailmichael.j.sherratt@manchester.ac.uk
lab head
Alexander Eckersley
contact affiliationUniversity of Manchester
contact emailalexander.eckersley@postgrad.manchester.ac.uk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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