PXD008450

PXD008450 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Tissue Microfibril Comparison - Structural and compositional diversity of fibrillin microfibrils in human tissues
Description	Fibrillin microfibrils are large supramolecular ECM assemblies which play different functional roles in different tissues. We aim to compare the ultrastructure and biological composition of fibrillin microfibrils purified from human eye, skin and cultured dermal fibroblasts. This will allow us to understand whether these their structure and compositions have evolved to suit the functions they play in different tissues.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:42:13.308.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD008450
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Alexander Eckersley
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Oxidation; Carbamidomethyl
Instrument	LTQ Orbitrap Elite

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2017-12-14 02:20:09	ID requested
1	2018-02-16 07:52:08	announced
2	2018-02-23 04:21:12	announced	Updated publication reference for PubMed record(s): 29453284.
⏵ 3	2024-10-22 04:42:14	announced	2024-10-22: Updated project metadata.

Publication List

10.1074/jbc.ra117.001483;
10.6019/PXD008450;
Eckersley A, Mellody KT, Pilkington S, Griffiths CEM, Watson REB, O'Cualain R, Baldock C, Knight D, Sherratt MJ, Structural and compositional diversity of fibrillin microfibrils in human tissues. J Biol Chem, 293(14):5117-5133(2018) [pubmed]

10.1074/jbc.ra117.001483;

10.6019/PXD008450;

Eckersley A, Mellody KT, Pilkington S, Griffiths CEM, Watson REB, O'Cualain R, Baldock C, Knight D, Sherratt MJ, Structural and compositional diversity of fibrillin microfibrils in human tissues. J Biol Chem, 293(14):5117-5133(2018) [pubmed]

Keyword List

curator keyword: Biological
submitter keyword: Human, microfibril, AFM, fibrillin, collagen, LC-MS/MS

curator keyword: Biological

submitter keyword: Human, microfibril, AFM, fibrillin, collagen, LC-MS/MS

Contact List

Michael Sherratt
contact affiliation	Division of Cell Matrix Biology & Regenerative Medicine, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK
contact email	michael.j.sherratt@manchester.ac.uk
lab head
Alexander Eckersley
contact affiliation	University of Manchester
contact email	alexander.eckersley@manchester.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/02/PXD008450
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/02/PXD008450

PRIDE project URI

Repository Record List

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