This study was conducted to: (1)comparative analysis of expression profiles of proteins in soybean leaf(a highly resistant line (Gantai-2-2) and a highly susceptible line (Wan 82-178) were exposed to Lamprosema indicate larval feedings for 0 h and 48 h);(2)explore how these proteins participated in the responses to resistance;(3) aim at resolving the soybeans’ constitutive and inducible defense mechanisms in response to Lamprosema indicate at the proteomic level.