The project investigated the changes in proteomics profile of canine flexor digitorum profundus tendons 28 days after tendon transection and surgical repair with (ASCs+BMP12) or without a stem cell and growth factor based treatment (repair only). Specifically, adipose-derived mesenchymal stromal cells together with BMP12 were delivered with a polymer scaffold consisting of multiple alternating layers of a heparin/fibrin-based delivery system and a polylactic co-glycolic acid (PLGA) scaffold. Non-operated tendons from contralateral digits were used as normal control (Normal).