PXD076855

PXD076855 is an original dataset announced via ProteomeXchange.

Title	Serum proteomics and metabolomics reveal novel noninvasive molecular signatures for hepatocellular carcinoma diagnosis
Description	This study aimed to identify and validate noninvasive serum protein and metabolite biomarkers for the early detection and prognostic assessment of hepatocellular carcinoma (HCC). In this study, we systematically analyzed serum proteomics and metabolomics across four cohorts, including healthy controls (Health) and patients with chronic hepatitis B (CHB), liver cirrhosis (LC), and HCC. Standardized sample handling protocols were applied, and high-resolution mass spectrometry combined with rigorous statistical analyses was used to identify differential proteins and metabolites.
HostingRepository	iProX
AnnounceDate	2026-04-10
AnnouncementXML	Submission_2026-04-10_01:20:11.140.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Lin Lin
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2026-04-10 01:18:54	ID requested
⏵ 1	2026-04-10 01:20:11	announced

Dataset with its publication pending

submitter keyword: biomarker, diagnosis, hepatocellular carcinoma, metabolites, proteomics, serum

Qishui Ou
contact affiliation	Department of Laboratory Medicine, The First Affiliated Hospital, Fujian Medical University
contact email	ouqishui@fjmu.edu.cn
lab head
Lin Lin
contact affiliation	Department of Laboratory Medicine, The First Affiliated Hospital, Fujian Medical University
contact email	812107870@qq.com
dataset submitter

iProX dataset URI