⮝ Full datasets listing
PXD072640
PXD072640 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | CRL4AMBRA1 mediated progesterone receptor degradation drives progestin resistance and represents a therapeutic vulnerability in endometrial cancer |
| Description | AMBRA1 ubiquitinates PR to ptomote progestin resistance in endometrial cancer |
| HostingRepository | iProX |
| AnnounceDate | 2026-01-04 |
| AnnouncementXML | Submission_2026-06-16_01:11:00.567.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yaru Sheng |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-01-05 01:05:55 | ID requested | |
| 1 | 2026-01-05 01:06:10 | announced | |
| ⏵ 2 | 2026-06-16 01:11:01 | announced | 2026-06-16: Add info |
Publication List
| Sheng Y, Ni T, Ding X, Huang J, Zhao X, Li X, Li Q, Wang J, Yang X, Zhang L, Zheng X, Cao D, Su R, Lu X, Hou J, Wang Y, -mediated progesterone receptor degradation drives progestin resistance and represents a therapeutic vulnerability in endometrial cancer. Int J Biol Sci, 22(9):4976-4996(2026) [pubmed] |
Keyword List
| submitter keyword: endometrial cancer, progesterone receptor, ubiquitination modification, medroxyprogesterone acetate resistance |
Contact List
| Yudong Wang | |
|---|---|
| contact affiliation | The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University |
| contact email | wangyudong@shsmu.edu.cn |
| lab head | |
| Yaru Sheng | |
| contact affiliation | The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University |
| contact email | shengyaru@sjtu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |




