⮝ Full datasets listing
PXD072469
PXD072469 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Crocins ameliorate experimental immune checkpoint inhibitor-related myocarditis by targeting the Hpx/Nrf2/HO-1 pathway |
| Description | Immune checkpoint inhibitors (ICIs) for cancer therapy may induce immune-related adverse events including myocarditis, which occurs infrequently but carries a high mortality rate. Crocins are the active constituents derived from Crocus sativus L. (Saffron), and have demonstrated various bioactivities including anti-tumor, anti-inflammation, anti-oxidation, anti-ischemia, anti-aging, and neuroprotection. |
| HostingRepository | iProX |
| AnnounceDate | 2025-12-27 |
| AnnouncementXML | Submission_2025-12-28_19:24:12.333.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Fangbo Zhang |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | (13)C labeled residue |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-12-28 19:23:45 | ID requested | |
| ⏵ 1 | 2025-12-28 19:24:12 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: crocins, Crocus sativus L., immune checkpoint inhibitor-related myocarditis, Hpx/Nrf2/HO-1 pathway |
Contact List
| Hongjun Yang | |
|---|---|
| contact affiliation | China Academy of Chinese Medical Sciences |
| contact email | hjyang@icmm.ac.cn |
| lab head | |
| Fangbo Zhang | |
| contact affiliation | Institute of Chinese Materia Medica , China Academy of Chinese Medical Sciences |
| contact email | fbzhang@icmm.ac.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
