⮝ Full datasets listing
PXD072330
PXD072330 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | The atlas of protein acetylation, 2-hydroxyisobutyrylation, and malonylation in developing cassava roots |
| Description | In this study, we constructed the first global proteomic atlas of Kac, Khib, and Kma modifications in developing cassava roots, identifying 11,253 Kac, 18,326 Khib, and 4,068 Kma sites across 5,165, 4,832, and 1,815 proteins, respectively. Comparative sequence analysis revealed conservation of Kac and Khib sites in histones across cassava, sugarcane, and rice, with higher sequence conservation observed in histone H2A and H4 compared to H2B. Functional enrichment demonstrated that PTM-modified proteins were predominantly involved in sucrose/starch metabolism, glycolysis/gluconeogenesis, pentose phosphate pathway, TCA cycle, pyruvate metabolism, and lignin biosynthesis, with the majority exhibiting multiple PTM co-occurrence. In addition, hundreds of modified proteins associated with stress response, hormone metabolism, and transcription factors were also identified, of which a few proteins displayed significant type-specific modification preferences. |
| HostingRepository | iProX |
| AnnounceDate | 2025-12-23 |
| AnnouncementXML | Submission_2025-12-22_19:21:43.047.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Zehong Ding |
| SpeciesList | scientific name: Manihot esculenta; NCBI TaxID: 3983; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-12-22 19:21:22 | ID requested | |
| ⏵ 1 | 2025-12-22 19:21:43 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: acetylation, 2-hydroxyisobutyrylation, malonylation |
Contact List
| Zehong Ding | |
|---|---|
| contact affiliation | Institute of Tropical Bioscience and Biotechnology |
| contact email | zehong3141@sina.com |
| lab head | |
| Zehong Ding | |
| contact affiliation | Institute of Tropical Bioscience and Biotechnology |
| contact email | zehong3141@sina.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
