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PXD071289

PXD071289 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleOptimization of methods for the quantitative analysis of global cell surface proteome and cell surface polarization
Descriptionhe application of our cell surface labeling and peptide enrichment workflow to MDCKII epithelial monolayers enabled large-scale quantification of apical versus basolateral domains, yielding over 2,100 proteins with 235 showing significant polarized distribution in agreement with known biology. This method offers high specificity for extracellular labeling and quantitative resolution of cell surface protein polarization, providing a powerful platform for studying epithelial biology and identifying extracellular epitopes relevant to diagnostics and therapeutic targeting.
HostingRepositoryiProX
AnnounceDate2025-11-26
AnnouncementXMLSubmission_2025-11-26_17:36:15.873.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterZoltan Szabo
SpeciesList scientific name: canis group; NCBI TaxID: 106178;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Exploris 240
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-11-26 17:35:59ID requested
12025-11-26 17:36:16announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: cell surface, biotin enrichment
Contact List
Zoltan Szabo
contact affiliationUniversity of Szeged
contact emailszabo.zoltan@med.u-szeged.hu
lab head
Zoltan Szabo
contact affiliationUniversity of Szeged
contact emailszabo.zoltan@med.u-szeged.hu
dataset submitter
Full Dataset Link List
iProX dataset URI