PXD071272

PXD071272 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Optimization of methods for the quantitative analysis of global cell surface proteome and cell surface polarization
Description	The application of our cell surface labeling and peptide enrichment workflow to MDCKII epithelial monolayers enabled large-scale quantification of apical versus basolateral domains, yielding over 2,100 proteins with 235 showing significant polarized distribution in agreement with known biology. This method offers high specificity for extracellular labeling and quantitative resolution of cell surface protein polarization, providing a powerful platform for studying epithelial biology and identifying extracellular epitopes relevant to diagnostics and therapeutic targeting.
HostingRepository	jPOST
AnnounceDate	2025-11-27
AnnouncementXML	Submission_2025-11-26_09:50:45.374.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zoltan Szabo
SpeciesList	scientific name: Canis; NCBI TaxID: 9611;
ModificationList	S-carboxamidomethyl-L-cysteine; alpha-amino acetylated residue; 2-pyrrolidone-5-carboxylic acid (Gln); CAMthiopropanoyl; L-methionine sulfoxide; deamidated L-asparagine
Instrument	instrument

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-11-26 09:50:41	ID requested
⏵ 1	2025-11-26 09:50:45	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: cell surface, biotinylation,

submitter keyword: cell surface, biotinylation,

Contact List

Zoltan Szabo
lab head
Zoltan Szabo
contact affiliation	University of Szeged
dataset submitter

Full Dataset Link List

jPOST dataset URI
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jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST004208/