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PXD070137

PXD070137 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSingle-cell transcriptome atlas reveals the underlying mechanism of kynurenic acid in regulation tumor immune microenvironment in glioblastoma
DescriptionWe performed 4D-DIA approach to quantified the proteome of GBM tissues from two groups. An average of 8880 quantified proteins were identified in each sample. In order to further explore the regulation of Kyna on GMB-resident T cells at the protein level, we performed 4D-DIA proteome analysis of CD45+Cd3e+CD8+ cells sorted from GMB in Kyna-treated mice and control mice.
HostingRepositoryiProX
AnnounceDate2025-10-30
AnnouncementXMLSubmission_2025-10-31_00:05:55.698.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterLiming Sun
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-10-31 00:05:42ID requested
12025-10-31 00:05:56announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: GMB, KYNA, 4D-DIA, Brain, CD8 T cells
Contact List
Rong Zeng
contact affiliationShanghai Clinical Research and Trial Center, ShanghaiTech University
contact emailzr@sibcb.ac.cn
lab head
Liming Sun
contact affiliationUniversity of Chinese Academy of Sciences
contact emailsunlm@ucas.ac.cn
dataset submitter
Full Dataset Link List
iProX dataset URI