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PXD069896

PXD069896 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe effect of ADAR1 depletion on mitochondrial proteins
DescriptionIn this study, we found that ADAR1 reduces the levels of double-stranded RNAs (dsRNAs) derived from both nuclear and mitochondrial transcripts. To elucidate how ADAR1 controls mitochondrial dsRNA (mt-dsRNA) accumulation, we performed quantitative mass spectrometry on mitochondrial protein fractions from wild-type and ADAR1-deficient cells, aiming to identify mitochondrial protein mediators involved in ADAR1-dependent dsRNA regulation.
HostingRepositoryPRIDE
AnnounceDate2026-01-23
AnnouncementXMLSubmission_2026-01-23_04:30:30.918.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHachung Chung
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-10-25 00:05:38ID requested
12026-01-23 04:30:31announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: None
Contact List
Hachung Chung
contact affiliationDepartment of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA
contact emailhc3070@cumc.columbia.edu
lab head
Hachung Chung
contact affiliationColumbia University
contact emailhchunglab@gmail.com
dataset submitter
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Dataset FTP location
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PRIDE project URI
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