PXD067835 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Quantitative proteomics analysis of Stra8-Pdcd5-/- mouse elongating spermatids |
| Description | In order to investigate the molecular mechanism of PDCD5 in the regulation of spermatids development, elongating spermatids from Pdcd5F/F and Stra8-Pdcd5-/- mice were collected for quantitative proteomics analysis using TMT-based liquid chromatography-tandem mass spectrometry (LC-MS/MS) approach. A total of 8730 proteins were quantified, and 512 proteins (p < 0.05, Foldchange > 1.5) were differentially expressed. Among these differential proteins, 58 proteins were downregulated (11%) and 454 proteins were upregulated (89%) in Stra8-Pdcd5-/- elongating spermatids. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-01-08 |
| AnnouncementXML | Submission_2026-01-08_06:43:18.305.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yueshuai Guo |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-08-28 07:07:27 | ID requested | |
| ⏵ 1 | 2026-01-08 06:43:18 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: PDCD5,Quantitative proteomics, TMT, Mouse, Elongating spermatids |
Contact List
| Xuejiang Guo |
|---|
| contact affiliation | State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, 211166, China. |
| contact email | guo_xuejiang@njmu.edu.cn |
| lab head | |
| Yueshuai Guo |
|---|
| contact affiliation | Nanjing Medical University |
| contact email | gys_706@163.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD067835 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD067835
- Label: PRIDE project
- Name: Quantitative proteomics analysis of Stra8-Pdcd5-/- mouse elongating spermatids
