PXD067447

PXD067447 is an original dataset announced via ProteomeXchange.

Title	Akkermansia muciniphila MucT – Polyphenols interactions.
Description	It is known that polyphenols can promote a healthy gut microbiota balance, which is beneficial in preventing metabolic diseases. Particularly, proanthocyanidins (PACs), a prominent dietary polyphenol, have been found to selectively increase the relative abundance of A. muciniphila. This symbiotic microorganism is known for supporting metabolic, immune, and gastrointestinal health. This project delves into the molecular and metabolic adaptation of A. muciniphila to dietary PACs. It sheds light on novel signaling mechanisms related to iron acquisition and regulation of xenosiderophore uptake in the presence of dietary PACs.
HostingRepository	PRIDE
AnnounceDate	2025-08-21
AnnouncementXML	Submission_2025-08-21_06:15:52.973.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sjef Boeren
SpeciesList	scientific name: Akkermansia muciniphila ATCC BAA-835; NCBI TaxID: 349741;
ModificationList	S-carboxamidoethyl-L-cysteine; acetylated residue; monohydroxylated residue; deamidated residue
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2025-08-18 00:51:42	ID requested
⏵ 1	2025-08-21 06:15:53	announced

Dataset with its publication pending

submitter keyword: xenosiderophores, Proanthocyanidins, microbiota,Akkermansia muciniphila, iron., Polyphenols

Sjef Boeren
contact affiliation	Wageningen University
contact email	sjef.boeren@wur.nl
lab head
Sjef Boeren
contact affiliation	Biochemistry
contact email	sjef.boeren@wur.nl
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD067447

PRIDE project URI

• PRIDE
  1. PXD067447
     1. Label: PRIDE project
     2. Name: Akkermansia muciniphila MucT – Polyphenols interactions.