PXD066485

PXD066485 is an original dataset announced via ProteomeXchange.

Title	Improvements to Casanovo, a deep learning de novo peptide sequencer
Description	Casanovo is a state-of-the-art deep learning model for de novo peptide sequencing from mass spec- trometry proteomics data. Here we report on a series of enhancements to Casanovo, aimed at improving the interpretability of the scores assigned to predicted peptides, generalizing the software for use in database search, speeding up training and prediction runtimes, and providing workflows and visual- ization tools to facilitate adoption of Casanovo and interpretation of its results. Our goal is to make Casanovo accurate and easy to use for applications such as metaproteomics, antibody sequencing, im- munopeptidomics, and discovery of novel peptide sequences in standard proteomics analyses. Casanovo is available as open source at https://github.com/Noble-Lab/casanovo. The raw data and search results can also be viewed at: https://limelight.yeastrc.org/limelight/d/pg/project/165
HostingRepository	PanoramaPublic
AnnounceDate	2025-07-23
AnnouncementXML	Submission_2025-07-23_11:31:09.038.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Chris Hsu
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090; scientific name: Homo sapiens; NCBI TaxID: 9606; scientific name: Saccharomyces cerevisiae; NCBI TaxID: 4932;
ModificationList	Carbamidomethyl
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2025-07-23 10:28:32	ID requested
⏵ 1	2025-07-23 11:31:09	announced

no publication

submitter keyword: Casanovo, de novo, DDA

William Noble
contact affiliation	University of Washington
contact email	wnoble@uw.edu
lab head
Chris Hsu
contact affiliation	University of Washington
contact email	chrhsu@uw.edu
dataset submitter

Panorama Public dataset URI