PXD064540
PXD064540 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Therapeutic effect and underlying mechanism of cell therapy on cyclophosphamide-induced premature ovarian insufficiency mouse model |
Description | An equivalent dosage of human umbilical cord-derived mesenchymal stem cell (HucMSC), adipose tissue-derived mesenchymal stem cell (ADSC), and SVF was orthotopically administered into a cyclophosphamide (CTX)-induced premature ovarian insufficiency (POI) mouse model. The therapeutic impacts were meticulously evaluated employing a suite of assays. The underlying mechanisms were investigated through RNA sequencing (RNA-seq) and mass spectrometry, offering insights into the cellular and molecular responses. |
HostingRepository | iProX |
AnnounceDate | 2025-05-31 |
AnnouncementXML | Submission_2025-06-03_00:22:44.638.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yingyi Zhang |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | LTQ Orbitrap |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2025-06-03 00:22:21 | ID requested | |
⏵ 1 | 2025-06-03 00:22:45 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: mesenchymal stem cells, stromal vascular fraction, premature ovarian insufficiency, female fertility preservation, oxidative stress |
Contact List
Songying Zhang | |
---|---|
contact affiliation | Sir Run Run Shaw Hospital (SRRSH), affiliated with Zhejiang University School of Medicine |
contact email | zhangsongying@zju.edu.cn |
lab head | |
Yingyi Zhang | |
contact affiliation | Sir Run Run Shaw Hospital (SRRSH), affiliated with Zhejiang University School of Medicine |
contact email | zhangyingyi@zju.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |