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PXD064540

PXD064540 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTherapeutic effect and underlying mechanism of cell therapy on cyclophosphamide-induced premature ovarian insufficiency mouse model
DescriptionAn equivalent dosage of human umbilical cord-derived mesenchymal stem cell (HucMSC), adipose tissue-derived mesenchymal stem cell (ADSC), and SVF was orthotopically administered into a cyclophosphamide (CTX)-induced premature ovarian insufficiency (POI) mouse model. The therapeutic impacts were meticulously evaluated employing a suite of assays. The underlying mechanisms were investigated through RNA sequencing (RNA-seq) and mass spectrometry, offering insights into the cellular and molecular responses.
HostingRepositoryiProX
AnnounceDate2025-05-31
AnnouncementXMLSubmission_2025-06-03_00:22:44.638.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYingyi Zhang
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ Orbitrap
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-06-03 00:22:21ID requested
12025-06-03 00:22:45announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: mesenchymal stem cells, stromal vascular fraction, premature ovarian insufficiency, female fertility preservation, oxidative stress
Contact List
Songying Zhang
contact affiliationSir Run Run Shaw Hospital (SRRSH), affiliated with Zhejiang University School of Medicine
contact emailzhangsongying@zju.edu.cn
lab head
Yingyi Zhang
contact affiliationSir Run Run Shaw Hospital (SRRSH), affiliated with Zhejiang University School of Medicine
contact emailzhangyingyi@zju.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI