PXD064348

PXD064348 is an original dataset announced via ProteomeXchange.

Title	Plasmodium parasite proteomics of iron deficiency
Description	Iron deficiency anaemia and Plasmodium infection represent significant global health challenges with overlapping geographical distributions, particularly affecting pregnant women in Africa. Previous evidence suggests complex interactions between iron status and malaria susceptibility. However, the precise mechanisms and clinical implications of this relationship remain poorly understood. Here,we explored direct effects of iron chelation on cultured P. falciparum parasites through proteomic analyses, which was found to primarily affect processes involved in host cell invasion, protein export, and nutrient acquisition
HostingRepository	PRIDE
AnnounceDate	2026-01-14
AnnouncementXML	Submission_2026-01-13_16:34:43.946.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Samantha Emery
SpeciesList	scientific name: Plasmodium falciparum (isolate 3D7); NCBI TaxID: NEWT:36329;
ModificationList	amidated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2025-05-27 19:29:04	ID requested
⏵ 1	2026-01-13 16:34:44	announced

Dataset with its publication pending

submitter keyword: Plasmodium, DFO, proteomics, iron deficiency

Sant-Rayn Pasricha
contact affiliation	Infection and Global Health, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia. Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia. Diagnostic Haematology, The Royal Melbourne Hospital, Melbourne, Victoria, Australia.
contact email	pasricha.s@wehi.edu.au
lab head
Samantha Emery
contact affiliation	Population Health and Immunity, Walter and Eliza Hall Institute of Medical Research
contact email	emery.s@wehi.edu.au
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD064348

PRIDE project URI

• PRIDE
  1. PXD064348
     1. Label: PRIDE project
     2. Name: Plasmodium parasite proteomics of iron deficiency