PXD062672

PXD062672 is an original dataset announced via ProteomeXchange.

Title	Proteomic analysis of human lung cancer and paracancer tissues
Description	The treatment of LUAD mainly includes surgery, radiotherapy and chemotherapy. However, the clinical population of LUAD chemotherapy drugs is limited, and patients inevitably have the problem of drug resistance. The development of LUAD therapeutic drugs can provide more treatment strategies for patients, and the study of biomarkers is an effective way to provide potential therapeutic targets. In this study, by comparing the proteome of cancer, paracancer and distant paracancer tissues of LUAD patients, it was found that SEC61B, AKR1C2, NOP10, SLC9A3R1, VAC14, PRPF6, DNAJC10 and SRP72 were eight potential LUAD protein markers. Among them, DNAJC10 has a cancer-promoting effect in LUAD, and its high expression is not conducive to patient survival.
HostingRepository	iProX
AnnounceDate	2025-04-07
AnnouncementXML	Submission_2025-04-07_00:53:05.478.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zhuoru He
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2025-04-07 00:52:40	ID requested
⏵ 1	2025-04-07 00:53:05	announced

Dataset with its publication pending

submitter keyword: Human lung tissues,Q Exactive HF,DIA,LC-MS

Zhongqiu Liu
contact affiliation	Guangzhou University of Chinese Medicine
contact email	liuzq@gzucm.edu.cn
lab head
Zhuoru He
contact affiliation	Guangzhou University of Chinese Medicine
contact email	hezhuoru@gzucm.edu.cn
dataset submitter

iProX dataset URI