PXD061596

PXD061596 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic changes in the colon of mice with epithelial specific deletion of Apc or Apc/Dhps
Description	C57BL/6 mice with a tamoxifen (TAM)-inducible disruption of Apc (CDX2P-CreERT2;Apc fl/fl) or Apc and Dhps (CDX2P-CreERT2;Apc fl/fl;Dhps fl/fl) were injected or not with one intraperitoneal injection 4.5 mg/kg TAM. After 35 days, the following colon biopsies were harvested: normal tissues from mice that did not receive TAM, non-tumor tissues from mice treated with TAM, and tumors from mice treated with TAM. Biopsies from 5 mice were collected for the following sample groups: (1) Apc Control; (2) Apc/Dhps Control; (3) Apc+TAM non-tumor; (4) Apc/Dhps+TAM non-tumor; (5) Apc+TAM tumor; (6) Apc/Dhps+TAM tumor
HostingRepository	PRIDE
AnnounceDate	2025-09-12
AnnouncementXML	Submission_2025-09-11_16:38:39.550.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kristie Lindsey Rose
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	oxidized residue; iodoacetamide derivatized residue
Instrument	Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-03-07 16:42:59	ID requested
⏵ 1	2025-09-11 16:38:39	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: Polyamines
Hypusine
Translation
Colorectal cancer
Apc
Tumorigenesis
Proteomics

submitter keyword: Polyamines

Hypusine

Translation

Colorectal cancer

Apc

Tumorigenesis

Proteomics

Contact List

Kristie Lindsey
contact affiliation	Vanderbilt University Proteomics Core
contact email	kristie.rose@vanderbilt.edu
lab head
Kristie Lindsey Rose
contact affiliation	Vanderbilt university
contact email	kristie.rose@vanderbilt.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD061596
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD061596

PRIDE project URI

Repository Record List

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