⮝ Full datasets listing
PXD061094
PXD061094 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomics of bacterial and ovarian cancer ascites extracellular vesicles |
| Description | Extracellular vesicles (EVs) are present in body fluids, and they can be disease biomarkers. Emerging evidence has proven that EVs are released not only from mammalian cells but also from bacteria. Ovarian cancer has a dismal prognosis because of difficulties in early detection. This study aimed to identify bacterial EV (BEV) proteins associated with ovarian cancer. Fifteen patients with ovarian cancer or benign tumors were recruited, and EVs were isolated from the ascites. BEVs were recovered from seven in vitro-cultured strains of bacteria present in the vaginal microbiota, and LC-MS/MS analysis was performed. The detected peptide data were annotated to both human and bacterial references, and the human data showed that the profiles of cancer EVs were distinct from those of patients with benign tumors. |
| HostingRepository | MassIVE |
| AnnounceDate | 2025-11-14 |
| AnnouncementXML | Submission_2025-11-14_21:47:07.917.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Kosuke Yoshida |
| SpeciesList | scientific name: Lactobacillus gasseri; NCBI TaxID: 1596; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | instrument model |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-02-23 04:41:58 | ID requested | |
| ⏵ 1 | 2025-11-14 21:47:08 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: bacteria, ovarian cancer, ascites, extracellular vesicles, DatasetType:Proteomics |
Contact List
| Akira Yokoi | |
|---|---|
| contact affiliation | Nagoya University |
| contact email | ayokoi@med.nagoya-u.ac.jp |
| lab head | |
| Kosuke Yoshida | |
| contact affiliation | Nagoya University |
| contact email | yoshida.kosuke.n7@f.mail.nagoya-u.ac.jp |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v09/MSV000097198/ |
