PXD059504

PXD059504 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Drug Repurposing Identifies Proteasome Inhibitors as Antiproliferative Agents Counteracting Inflammation-Driven Chemoresistance in Triple-Negative Breast Cancer Organoids
Description	Triple-negative breast cancer (TNBC) is an aggressive subtype with limited treatment options, characterized by high relapse rates and poor survival outcomes due to chemoresistance. This study aimed to repurpose FDA-approved drugs to overcome chemoresistance in TNBC and elucidate their mechanisms of action.
HostingRepository	jPOST
AnnounceDate	2026-01-06
AnnouncementXML	Submission_2026-01-05_07:00:16.772.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sittiruk Roytrakul
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide
Instrument	instrument

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-07 05:21:10	ID requested
⏵ 1	2026-01-05 07:00:17	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: Triple-Negative Breast Cancer (TNBC)
Chemoresistance
Proteasome Inhibitors
Patient-Derived Organoids
Drug Repurposing

submitter keyword: Triple-Negative Breast Cancer (TNBC)

Chemoresistance

Proteasome Inhibitors

Patient-Derived Organoids

Drug Repurposing

Contact List

Assoc. Prof. Rossukon Kaewkhaw
lab head
Sittiruk Roytrakul
contact affiliation	BIOTEC
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003533/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003533/