PXD059455 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Wastewater metaproteomics: tracking microbial and human protein biomarkers |
| Description | This study showcases the application of metaproteomics to generate a comprehensive proteomic profile from municipal wastewater. We developed a streamlined sample preparation protocol and a data-processing pipeline that integrates de novo sequencing to customize large public sequence databases for in-depth metaproteomic analysis. Wastewater samples collected over three months from two urban locations revealed a diverse range of microbes, including common gut bacteria and opportunistic pathogens. Furthermore, approximately 200 human proteins were identified, including potential health and disease biomarkers such as immunoglobulins, uromodulin, and cancer-associated markers. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-12-15 |
| AnnouncementXML | Submission_2025-12-15_11:05:59.454.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Martin Pabst |
| SpeciesList | scientific name: Escherichia coli; NCBI TaxID: NEWT:562; |
| ModificationList | monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-01-06 00:50:02 | ID requested | |
| ⏵ 1 | 2025-12-15 11:05:59 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: metaproteomics, wastewater-based epidemiology, wastewater, gut microbes, biomarkers |
Contact List
| Martin Pabst |
|---|
| contact affiliation | Department of Biotechnology, TU Delft, The Netherlands |
| contact email | m.pabst@tudelft.nl |
| lab head | |
| Martin Pabst |
|---|
| contact affiliation | TUD |
| contact email | m.pabst@tudelft.nl |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD059455 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD059455
- Label: PRIDE project
- Name: Wastewater metaproteomics: tracking microbial and human protein biomarkers
