PXD059272

PXD059272 is an original dataset announced via ProteomeXchange.

Title	Structural Insights into the Role of Eukaryotic Translation Initiation Factor 3 (eIF3) in Translation Mediated by the Hepatitis C Virus IRES
Description	Cross-linking mass spectrometry was conducted to determine the positions of the non-core subunits (eIF3b, eIF3d, eIF3g, eIF3i, and eIF3j) of eIF3, that were not observed in cryo-EM densities, during elongation. For this analysis, the HCV IRES-initiated uORF2-stalled 80S ribosome was prepared from the in vitro translation system coupled with transcription, identical to the preparation used for the cryo-EM sample.
HostingRepository	jPOST
AnnounceDate	2025-11-20
AnnouncementXML	Submission_2025-11-19_19:51:26.395.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Koshi Imami
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine; alpha-amino acetylated residue; L-methionine sulfoxide
Instrument	Orbitrap Eclipse

Revision	Datetime	Status	ChangeLog Entry
0	2024-12-27 00:00:01	ID requested
⏵ 1	2025-11-19 19:51:26	announced

Dataset with its publication pending

submitter keyword: XL-MS, ribosome, IRES

Takuhiro Ito
lab head
Koshi Imami
contact affiliation	RIKEN
dataset submitter

jPOST dataset URI

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003529/