PXD057477

PXD057477 is an original dataset announced via ProteomeXchange.

Title	Expression of ABC transporters negatively correlates with ectoine biosynthesis in Halomonas campaniensis under NaCl and ultraviolet mutagenesis treatments revealed by transcriptomic and proteomics combined analysis
Description	Halomonas species are renowned for their production of organic compatible solutes, particularly ectoine. However, the identification of key regulatory genes governing ectoine production in Halomonas remains limited. In this study, we conducted a combined transcriptome-proteome analysis to unveil additional regulatory genes influencing ectoine biosynthesis, particularly under ultraviolet (UV) and salt conditions. NaCl induction resulted in a 20-fold increase, while UV treatment led to at least 2.5-fold increases in ectoine production. The number of overlapping genes between transcriptomic and proteomic analyses for three comparisons, i.e., non-UV with NaCl (UV0-NaCl) vs. non-UV without NaCl (UV0), UV strain 1 (UV1-NaCl) vs. UV0-NaCl, and UV strain 2 (UV2-NaCl) vs. UV0-NaCl were 137, 19, and 21, respectively. The overlapped Gene Ontology (GO) enrichments between transcriptomic and proteomic analyses include ATPase-coupled organic phosphonate, phosphonate transmembrane transporter activity, and ATP-binding casse
HostingRepository	iProX
AnnounceDate	2024-11-02
AnnouncementXML	Submission_2024-11-03_23:50:29.221.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yanbing Lin
SpeciesList	scientific name: Halomonas; NCBI TaxID: 2745;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2024-11-03 23:50:06	ID requested
⏵ 1	2024-11-03 23:50:29	announced

Dataset with its publication pending

submitter keyword: Ectoine, Halomonas, transcriptome, proteome, ultraviolet, and salt treatments

Derui Zhu
contact affiliation	Research Centre of Basic Medical Sciences, Medical College, Qinghai University
contact email	zhuderui2005@126.com
lab head
Yanbing Lin
contact affiliation	Agricultural High-tech Industrial Demonstration Zone, Yangling City, Shanxi Province,China
contact email	linyb2004@nwsuaf.edu.cn
dataset submitter

iProX dataset URI