⮝ Full datasets listing
PXD057380
PXD057380 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | The ER Thioredoxin-Related Transmembrane Protein TMX2 Controls Redox-Mediated Tethering of ER-Mitochondria Contacts (ERMCS) |
| Description | Our study demonstrates that ERMCS-localized TMX2 enhances the antioxidant activity of PRDX1/2 on TOM70, thereby preventing sulfenylation of TOM70 at C206 and regulating mitochondrial metabolism. |
| HostingRepository | jPOST |
| AnnounceDate | 2025-10-31 |
| AnnouncementXML | Submission_2025-10-30_08:00:06.661.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Chen |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; unknown modification; unknown modification |
| Instrument | instrument; instrument |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-10-30 23:39:05 | ID requested | |
| ⏵ 1 | 2025-10-30 08:00:07 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Endoplasmic reticulum (ER), mitochondria, redox, reactive oxygen species (ROS), Ca2+, TMX2, peroxiredoxin (PRDX), TOM70. |
Contact List
| Thomas Simmen | |
|---|---|
| lab head | |
| Chen | |
| contact affiliation | University of Alberta |
| dataset submitter | |
Full Dataset Link List
| jPOST dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003402/ |
