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PXD056632

PXD056632 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative profiling of STOichiometry by Resolvable Mass tags
DescriptionPost-translational modifications (PTMs) play important roles in modulating biological functions of proteins. Stoichiometry, which quantifies the modification percentage, is a critical factor for any given PTM. In this work, we developed a chemoproteomic strategy called “STO-MS” to systematically quantify the PTM stoichiometry in complex biological samples. This strategy employs a resolvable mass tag to differentiate proteoforms with different number of modifications, and utilizes liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) techniques to measure PTM stoichiometry at the proteomic level.
HostingRepositoryiProX
AnnounceDate2024-10-08
AnnouncementXMLSubmission_2024-10-08_20:32:07.058.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYuan Liu
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-10-08 20:31:53ID requested
12024-10-08 20:32:07announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: PTM, stoichiometry
Contact List
Chu Wang
contact affiliationPeking University
contact emailchuwang@pku.edu.cn
lab head
Yuan Liu
contact affiliationPeking University
contact emailwendao@pku.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI